Problematic blood clotting may contribute to Alzheimer's Disease

Alzheimer's diease continues to baffle scientists. Rockefeller University has released findigs from research that looks at the disease from a different angle.

ScienceDaily (July 14, 2010)  reports some new research results with Alzheimer's disease. It has longed been studied primarily as a disease of the neurons but research scientists at Rockefeller University have now shown how the disease process may be damaging the brain by choking off blood flow.

In experiments published June 10 in Neuron, scientists at Rockefeller University reveal that amyloid-β, which builds up around brain cells in Alzheimer's patients, interacts with a common blood clotting agent to increase clotting in the arteries that feed the brain. Such activity could cut off blood flow to neurons, suffocating them over time. A drug that interferes with that process could reduce the memory loss and dementia that are the most wrenching consequences of the disease, the findings suggest.
More

0 comment(s):